I can display a content with a specific metadata set but the content is generated with main metadata set (See ContentGenerator).
I guess we should add a parameter metadataSetName to get-content action in _wrapped-content.html pipeline (on CMS and Web plugins) :
            <map:match pattern="_wrapped-content.html">
                <map:act type="get-content">
                    <map:parameter name="id" value="{request-param:contentId}"/>
                    <map:parameter name="contentVersion" value="{request-param:contentVersion}"/>
                    <map:parameter name="metadataSetName" value="{request-param:metadataSetName}"/>
Or something like that...